Contains clindamycin antibiotic that kills acne-causing bacteria, unblocks pores, and prevents spots. Applied to skin for adult acne treatment.
How It Functions
Clindamycin binds bacterial 50S ribosomal subunit to inhibit protein synthesis, reducing Propionibacterium acnes and inflammation while preventing pore blockage. PMDC guidelines recommend as first-line for inflammatory acne.
Common Applications
Acne vulgaris in adults, inflammatory lesions, pustules, papules, facial bacterial infections.
Dosage Form
Topical gel (10g); apply thin layer to clean affected areas.
How To Use
Cleanse skin, apply pea-sized amount twice daily to spots. Rub gently; wash hands.
Dosage
Thin film 1-2 times daily as prescribed; complete full course.
Potential Side Effects
Very common: Skin irritation (burning, itching, peeling, dryness), hives, seborrhea. Uncommon: Diarrhea, nausea. Rare: Folliculitis, eye stinging/pain, stomach ache, contact dermatitis.
Key Warnings and Precautions
Stop for severe/bloody diarrhea (pseudomembranous colitis risk). Avoid eyes/mouth/nose; rinse contact. Unpleasant taste near mouth. Don’t stop early. Pregnancy: Consult physician.
When It’s Not Suitable (Contraindications)
Allergy to clindamycin/lincomycin/ingredients; history of inflammatory bowel disease or antibiotic colitis.
Drug Interactions
Keratolytics (irritation), neuromuscular blockers (systemic), erythromycin (antagonism), vitamin K antagonists (bleeding).
In Case of Overdose
Unlikely topically; rinse area, seek care if systemic symptoms.
Missed Dose
Apply when remembered; don’t double dose.
Storage and Disposal
Room temperature, away from light/heat. Pharmacy disposal for expired.
Quick Tips
Apply to dry skin post-cleansing. Use sunscreen. Moisturize if dry. Finish treatment.
Doctor Review
Dermatologists like Dr. Sana Khalid use for moderate acne, effective against resistant strains but monitor colitis risk; often combined with benzoyl peroxide.
Laboratory Screening
Stool tests if diarrhea; allergy patch testing.
FAQs
What is Acsolve for? Acne via bacterial kill and pore clearance. Application? Thin layer 1-2x daily. Pregnancy safe? Consult doctor. Storage? Room temp, dark/dry. Side effects? Irritation, rare GI. Avoid if? Clindamycin allergy, bowel history.
Disclaimer: Product information only, not medical advice. Consult Pakistani physician before use. Stop for severe diarrhea. Store room temperature, away from light.
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