Barilol

Description Barilol Tablets 2.5mg contain Bisoprolol Fumarate, a cardioselective beta-1 blocker used to treat hypertension and angina pectoris. It works by blocking beta-1 receptors in the heart, reducing the effects of catecholamines that cause faster and stronger heartbeats. This slows heart rate, lowers blood pressure, and eases the heart’s workload, improving efficiency in pumping blood. As a low-dose tablet, it’s ideal for initial therapy in adults, often combined with lifestyle changes like diet and exercise.

Ingredients Bisoprolol Fumarate 2.5mg.

Drug Class Beta-Blocker / Cardioselective Beta-1 Adrenergic Blocker / Antihypertensive.

Dosage Form Tablet (1 strip = 7 tablets).

Uses Barilol Tablets are prescribed for:

• High blood pressure (hypertension) management.
• Angina pectoris (chest pain from reduced heart blood flow).
• Stable chronic heart failure (as adjunct therapy).
• Prevention of cardiovascular events like heart attack or stroke.
• Adjunct in post-myocardial infarction care.

Doctor’s Review Cardiologists often start with Barilol for its selectivity and tolerability in early hypertension. As one cardiologist points out: “Barilol at 2.5mg is a smart entry point for blood pressure control, minimizing side effects while effectively protecting the heart. It’s particularly useful for patients with mild cases, but regular monitoring ensures safe titration.”

Dosage (Follow physician’s instructions — typical guideline)

• Adults: Start with 2.5mg once daily, with or without food.
• May increase to 5mg, 7.5mg, or 10mg daily after 1-2 weeks based on response.
• Heart failure: Begin at 1.25mg daily; titrate slowly to 10mg max.
• Maximum: 20mg daily; reduce in kidney/liver impairment.
• Do not stop abruptly—taper to avoid rebound effects.

In Case of Overdose Overdose can cause severe bradycardia, hypotension, heart block, or bronchospasm. Seek emergency care immediately. Symptoms include fainting, slow pulse, or breathing difficulty. Treatment involves supportive measures like IV fluids, atropine for heart rate, or glucagon; hemodialysis is ineffective.

Missed Dose Take as soon as remembered unless close to the next dose. Do not double up to prevent excessive heart rate slowing. Resume your schedule and inform your doctor if misses are common.

How to Use

• Swallow tablet whole with water, at the same time daily for consistency.
• Can take with or without food; morning dosing helps monitor effects.
• Monitor blood pressure and pulse regularly (aim for >50 bpm).
• Combine with a heart-healthy diet and activity as advised.
• Rise slowly from sitting to avoid dizziness.

When Not to Use Avoid Barilol if:

• Allergic to Bisoprolol Fumarate or excipients.
• Severe asthma or chronic obstructive pulmonary disease (COPD).
• Severe peripheral arterial circulatory disorders (e.g., Raynaud’s syndrome).
• Acute heart failure, cardiogenic shock, or second/third-degree AV block.
• Sick sinus syndrome or untreated pheochromocytoma.

Side Effects Common:

• Tiredness, weakness, dizziness, headache.
• Cold hands/feet, low blood pressure.
• GI issues (nausea, vomiting, diarrhea, constipation).

Uncommon / Severe (Stop and seek medical help):

• Sleep disturbances, depression, breathing problems.
• Muscle cramps/weakness, irregular heartbeat.
• Worsening heart failure (chest pain, swelling, shortness of breath).

Precautions & Warnings

• May alter blood sugar levels or mask hypoglycemia signs (e.g., rapid pulse)—monitor closely if diabetic.
• Inform surgeons/dentists of use; may need to pause before procedures.
• Can reduce alertness—avoid driving or machinery until adjusted.
• Watch for heart failure signs like swelling or weight gain; report promptly.
• Use cautiously in elderly or those with thyroid issues.

Drug Interactions

• Calcium channel blockers (e.g., verapamil, diltiazem): Enhance heart-slowing effects.
• Antiarrhythmics (e.g., amiodarone, disopyramide, flecainide): Risk of bradycardia.
• Antidepressants (e.g., imipramine, amitriptyline): May amplify hypotension.
• NSAIDs (e.g., ibuprofen, diclofenac): Reduce antihypertensive efficacy.
• Sympathomimetics (e.g., adrenaline) or mefloquine: Counteract beta-blockade.

Food Interactions

• Take with or without meals; no major restrictions.
• Avoid excessive salt to support blood pressure control.
• Limit alcohol—it can worsen dizziness or low pressure.

Storage/Disposal

• Store at room temperature (15-30°C), away from direct light and heat.
• Keep in original strip, out of reach of children.
• Dispose via pharmacy returns; do not flush.

Quick Tips

• Check pulse before doses—alert doctor if below 50 bpm.
• Wear a medical alert bracelet for emergencies.
• Log blood pressure readings for appointments.
• Stay active but ease into exercise.
• Hydrate well to counter dry mouth or fatigue.

Disclaimer This information is provided for educational purposes only and does not replace medical advice. Use only under the supervision of a licensed physician. Do not self-medicate.