Description
Ceftazidime is a third-generation cephalosporin antibiotic administered via injection. It works by inhibiting bacterial cell wall synthesis, leading to bacterial death or growth inhibition. It is intended for bacterial infections only and does not treat viral illnesses such as flu or the common cold.
Ingredients
Ceftazidime
Drug Class
Cephalosporin Antibiotic (3rd Generation, Beta-lactam).
Dosage Form
Injection (Vial)
Uses
Commonly used for bacterial infections such as:
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Pneumonia and other lower respiratory tract infections.
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Septicemia and bloodstream infections.
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Infections of skin, soft tissue, bone, and joints.
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Urinary tract infections.
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Abdominal and gynecologic infections.
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Infections in immunocompromised or critically ill patients.
Dosage
Administered intravenously (IV) or intramuscularly (IM), typically every 8 to 12 hours. Dose and duration are determined by infection severity and clinical status.
In Case of Overdose
May lead to neurological effects such as seizures or confusion. Supportive medical management is required in such cases.
Missed Dose
Administered by healthcare personnel; missed dose is unlikely. If using in home care settings, follow clinical instructions strictly.
How to Use
Reconstituted and administered by injection into a muscle or vein. Use immediately after preparation if possible. Inspect for discoloration or particulate matter before use.
When Not to Use
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Known hypersensitivity to ceftazidime or other cephalosporins.
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History of severe allergic reactions to beta-lactam antibiotics.
Side Effects
Common:
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Pain or redness at injection site.
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Stomach discomfort.
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Rash or itching.
Less common:
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Changes in liver or kidney markers.
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Reduction in white blood cells.
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Fungal overgrowth (e.g., oral or vaginal candidiasis).
Precautions & Warnings
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Monitor kidney and liver function during prolonged use.
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Use cautiously in patients with colitis or bleeding disorders.
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May interfere with certain laboratory tests (e.g., Coombs test).
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May impair live vaccine performance.
Drug Interactions
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Other antibiotics from the beta-lactam class.
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High-dose diuretics may increase renal strain.
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May reduce efficacy of live bacterial vaccines (e.g., oral typhoid).
Food Interactions
Not applicable for injectable formulation.
Storage / Disposal
Store vials at room temperature away from heat and moisture. Prepared solutions should be used as per guidelines or discarded safely. Keep away from children and unauthorized access.
Control Drug
No
Quick Tips
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Complete the full course as instructed in clinical settings.
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Inform healthcare personnel about any past drug allergies.
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Report unusual rashes or breathing issues immediately.
Doctor’s Review
Dr. Ayesha Rahman, Consultant Infectious Disease Specialist, notes:
“Ceftazidime remains a key option in hospital-acquired infections and resistant gram-negative cases. Regular renal monitoring ensures safe administration in long-term or high-dose therapy.”
Disclaimer
This profile is for informational purposes and does not replace medical consultation. Administration should follow licensed healthcare supervision only.
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