Ezita (10mg) 10 Tablets

Manufacturer: Getz Pharma (Pvt.) Ltd.
Generic Name: Ezetimibe 10mg

Ezita 10mg Tablet contains Ezetimibe, a cholesterol absorption inhibitor. It works in the small intestine by blocking the NPC1L1 protein, which is responsible for absorbing dietary cholesterol. By limiting cholesterol uptake, the medicine lowers LDL (bad cholesterol) and total cholesterol levels in the blood, making it useful for managing high cholesterol and reducing cardiovascular risk.

Ingredients

• Ezetimibe 10mg.

Drug Class

Cholesterol absorption inhibitor (statin-adjunct).

Uses

Ezita (Ezetimibe 10mg) is commonly prescribed for:

• Lowering high cholesterol levels when diet and lifestyle changes alone are insufficient.

• Treating heterozygous familial hypercholesterolemia (genetic high cholesterol disorder).

• Reducing the risk of heart disease and stroke by improving cholesterol profile.

• Combination therapy with statins to enhance cholesterol reduction.

• Alternative therapy for patients unable to tolerate statins.

In Case of Overdose

Possible symptoms include abdominal pain, diarrhea, and changes in liver enzymes. Medical attention should be sought immediately.

When Not to Use

• Known hypersensitivity to Ezetimibe.

• Moderate to severe liver disease.

• During pregnancy or breastfeeding unless clearly prescribed.

• Patients with sitosterolemia (rare inherited lipid disorder).

Side Effects

Possible side effects may include:

• Muscle pain.

• Diarrhea or abdominal pain.

• Joint pain or fatigue.

• Elevated liver enzymes.

• Allergic reactions (rash, itching).

• Rarely, severe muscle breakdown (rhabdomyolysis) when combined with other medicines.

Precautions & Warnings

• Monitor liver function regularly, especially when combined with statins.

• Caution in patients with gallbladder disease or gastrointestinal conditions.

• Patients with diabetes should monitor blood sugar levels closely.

• Avoid alcohol to reduce liver-related risks.

• Report any unexplained muscle pain, weakness, or dark urine immediately.

Drug Interactions

• Statins (e.g., atorvastatin, simvastatin): may increase risk of muscle problems.

• Cyclosporine: can increase drug levels and side effects.

• Bile acid sequestrants (e.g., cholestyramine): may reduce absorption.

• Fibrates: increase muscle toxicity risk.

• Rifampin and certain antifungals may alter drug levels.

Food Interactions

• Can be taken with or without food.

• Avoid grapefruit juice, which may increase drug concentration.

• Limit alcohol to protect liver function.

• Best combined with a low-fat, low-cholesterol diet.

Storage / Disposal

Store at room temperature, away from heat, sunlight, and moisture. Keep tightly sealed and out of children’s reach. Dispose of expired or unused tablets responsibly.

Doctor’s Review

Dr. Nadia Rahman, Consultant Cardiologist
“Ezita (Ezetimibe) is effective in lowering LDL cholesterol, particularly in patients who do not achieve sufficient results with diet and exercise alone. It is also valuable as an add-on therapy with statins. Patients should have their liver function monitored during use, and any unusual muscle pain must be reported immediately. For long-term cardiovascular protection, Ezita works best when paired with lifestyle modifications, including a healthy diet and regular physical activity.”

Disclaimer

This information is provided for educational purposes only. It outlines the general product profile of Ezita as used in Pakistan. It is not a prescription and should not replace medical consultation. Always seek guidance from a qualified doctor or pharmacist before using this medicine.