Description
NO-SPA Injection contains Drotaverine Hydrochloride, an antispasmodic drug that relaxes smooth muscles by inhibiting the enzyme Phosphodiesterase (PDE) IV. This action increases cAMP levels in the muscle cells, leading to muscle relaxation and relief from pain caused by spasms in the gastrointestinal, urinary, and reproductive systems.
Ingredients
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Drotaverine Hydrochloride 40mg/2ml
Drug Class
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Antispasmodic
Dosage Form
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Injection (Intramuscular or Intravenous)
Uses
Doctors prescribe NO-SPA Injection for:
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Severe abdominal cramps
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Menstrual pain
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Pain caused by kidney stones or gallstones
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Gastrointestinal colic (stomach and intestinal spasms)
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Cervical spasm and labor pain during childbirth
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Urinary tract spasms
Dosage
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Adults: 40–80mg (1–2 ampoules) given intramuscularly or intravenously, as prescribed.
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Children: Dosage must be adjusted by the doctor based on age and weight.
Overdose:
May cause nausea, dizziness, vomiting, low blood pressure, drowsiness, or irregular heartbeat. Seek immediate medical attention.
Missed Dose:
As this is usually given by a healthcare provider, missed doses are unlikely. If self-administered, consult your doctor before taking another dose.
How to Use
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Administered intramuscularly or intravenously by a trained healthcare professional.
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Do not self-inject without medical supervision.
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Follow your doctor’s instructions carefully regarding dose and frequency.
When Not to Use
Avoid NO-SPA Injection if you have:
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Allergy to Drotaverine or similar medicines
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Severe liver, kidney, or heart disease
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Pregnancy (unless prescribed by a doctor)
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Paralytic ileus or toxic megacolon
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Prostate enlargement causing urinary retention
Side Effects
Possible side effects include:
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Nausea, vomiting
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Dizziness, headache
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Low blood pressure
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Fast or irregular heartbeat
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Rash, itching, or swelling of face/lips/eyelids
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Breathing difficulty
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Injection site pain or redness
Precautions & Warnings
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Inform your doctor if you have liver, kidney, or heart problems.
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Use with caution in elderly patients.
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Avoid alcohol while on this treatment.
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Only use under medical supervision, especially in pregnancy or during labor.
Drug Interactions
Drotaverine may interact with:
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Levodopa (reduces effectiveness, may worsen Parkinson’s symptoms)
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Certain painkillers
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Antimuscarinic medicines
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Benzodiazepines
Storage & Disposal
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Store below 25°C in a dry place, away from sunlight.
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Keep out of reach of children.
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Do not use if the ampoule is damaged or past the expiry date.
Quick Tips
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Always let your doctor know if you are pregnant or breastfeeding.
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Do not self-inject; this medicine should be given by a trained professional.
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If dizziness occurs, avoid driving or operating machinery.
Doctor’s Overview — Dr. Farah Ahmed, MBBS, FCPS
No-Spa injection is used to give quick relief from strong period cramps and muscle spasms during labor. It works by relaxing the muscles. This injection should only be given by a doctor or nurse to make sure it is used safely.
Disclaimer
This overview is for educational purposes only. No-Spa injection is a prescription medicine and should be used only under the guidance of a qualified healthcare professional.
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