Poze met

Description

Poze Met 15mg/500mg Tablet is an oral medication designed for the management of type 2 diabetes, particularly in individuals who are overweight. It combines two active agents: pioglitazone, which enhances insulin sensitivity in tissues, and metformin, which reduces glucose production in the liver and improves insulin utilization. This combination helps in regulating blood sugar levels without including insulin. It belongs to the classes of thiazolidinediones (glitazones) for pioglitazone and biguanides for metformin.

Ingredients

• Pioglitazone 15 mg
• Metformin 500 mg

Dosage Form

• Tablet

Pack Details

• Brand: AGP
• Prescription: Required
• Pack Size: 2 strips of 7 tablets each (2×7’s)
• Price: Rs. 10.93 per tablet; Rs. 76.50 per pack (discounted from Rs. 85)

Uses

This medication is primarily indicated for:

• Controlling type 2 diabetes in overweight adults when diet and exercise alone are insufficient.

Expert Advice

• Do not use if you have a known allergy to pioglitazone, metformin, or any excipients.
• Seek medical advice if you are pregnant, planning pregnancy, or breastfeeding; if you have gastrointestinal issues; or if you have a history of liver, kidney, heart conditions, or bladder cancer.
• Inform your healthcare provider about all other medications you are using.
• Watch for signs of bone weakness or respiratory issues like shortness of breath.
• Maintain consistent meal times to stabilize blood glucose.
• Adhere strictly to the prescribed schedule and dosage.
• Be aware that weight gain may occur as a potential effect.

Side Effects

Possible adverse effects include:

• Visual impairments
• Upper respiratory tract infections Consult a healthcare professional if these or other symptoms arise.

Precautions & Warnings

• Pregnancy: Consult a healthcare provider prior to use.
• Lactation: Generally not recommended for breastfeeding individuals; seek professional guidance.
• Driving: Avoid operating vehicles if the medication impairs your alertness.
• Alcohol: Refrain from alcohol consumption while using this medication.
• Additional Precautions: Monitor regularly for heart-related issues. Use with caution in those with liver or heart conditions. Risk of lactic acidosis exists, especially with overdose—symptoms may include stomach pain, dizziness, breathing difficulties, muscle pain, or irregular heart rhythm. Long-term use might lead to vitamin B12 deficiency, potentially causing anemia (e.g., fatigue, pallor). Not advised for those with advanced liver disease like cirrhosis. Adjustments may be needed when used with thyroid medications or steroids.

Contraindications

Avoid use in cases of:

• Liver dysfunction
• Heart failure or prior history of heart failure

How to Use

Take as directed by a healthcare professional, typically with meals to minimize stomach upset. Do not discontinue without guidance. If a dose is missed, take it when remembered unless close to the next scheduled dose—do not double up. Maintain regular meals and physical activity to support blood sugar control.

In Case of Overdose

Overdose may lead to lactic acidosis or low blood sugar symptoms like dizziness, sweating, or palpitations. Seek immediate medical help.

Missed Dose

Resume the regular schedule without doubling; take the missed dose if remembered early.

Food Interactions

No specific food interactions noted, but consistent meal timing is essential. Avoid skipping meals to prevent blood sugar fluctuations.

Storage/Disposal

Store at room temperature, away from moisture and heat. Dispose of expired or unused tablets responsibly per local guidelines.

Related Lab Tests

• Fasting Blood Glucose
• Glycated Hemoglobin (HbA1c)

FAQs

What class of medications does this belong to? Pioglitazone is a thiazolidinedione (glitazone), while metformin is a biguanide. Together, they enhance insulin action and reduce glucose production.

Can it lead to hypoglycemia? Hypoglycemia is possible but uncommon; it’s more likely if combined with other diabetes treatments. Carry a sugar source for symptoms like lightheadedness.

What if a dose is forgotten? Take it upon recollection, but skip if nearing the next dose. Avoid doubling.

Does skipping meals affect it? Yes, it may cause low blood sugar symptoms such as heart palpitations or dizziness. Regular meals are crucial.

Might it cause fluid retention? Yes, ankle swelling or lung fluid buildup (leading to breathlessness) can occur.

Is it suitable for polycystic ovary syndrome (PCOS)? Metformin component may help regulate cycles in PCOS, but use only under medical supervision.

Does it contain hormones or insulin? No, it amplifies insulin’s effects without being insulin or a hormone.

Can it interact with thyroid or steroid drugs? Dose adjustments might be needed; discuss with a provider, as steroids can sometimes induce diabetes.

What is lactic acidosis, and is it a risk? It’s a rare, serious buildup of lactic acid, potentially from overdose. Symptoms include nausea, weakness, or rapid breathing—seek urgent care.

How long should treatment last? Follow the prescribed duration; prolonged use may require B12 monitoring to prevent deficiency.

Could it cause weight changes? Weight loss is more common due to reduced appetite, though bloating might occur. It’s not for weight management alone.

Is it safe with liver conditions? Safe for some like fatty liver or certain hepatitis, but avoid in cirrhosis due to lactic acidosis risk.

Doctor’s Review

Dr. Raj Patel (Endocrinologist): “Poze Met 15mg/500mg Tablet acts as a combination therapy for type 2 diabetes management, blending pioglitazone to improve insulin sensitivity and metformin to lower hepatic glucose output. It supports blood sugar regulation, especially in overweight individuals, and may offer benefits in conditions like PCOS through enhanced insulin function.”

Disclaimer

This product profile is intended solely for informational and educational purposes. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before initiating, altering, or discontinuing any medication. The details provided may not encompass all potential precautions, interactions, side effects, or contraindications. Use this information responsibly and discuss any concerns with your doctor.