Description
Progynova Tablets 2mg contain Estradiol Valerate, a synthetic form of the naturally occurring female hormone estradiol. Estradiol Valerate is used as part of hormone replacement therapy (HRT) for women who have stopped producing estrogen due to menopause or the removal of their ovaries (oophorectomy). By replacing the natural estrogen, Progynova alleviates symptoms of menopause such as hot flashes, night sweats, vaginal dryness, and irritability. Additionally, it helps prevent bone loss (osteoporosis) that can occur after menopause. Progynova does not inhibit ovulation, and it has little effect on endogenous hormone production.
Primary Uses
Progynova is used for:
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Hormone Replacement Therapy (HRT): To treat menopausal symptoms after the cessation of monthly bleeding or following surgical removal of the ovaries (oophorectomy).
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Osteoporosis Prophylaxis: Used to prevent bone loss after menopause.
Indications
Progynova is indicated for:
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The treatment of postmenopausal symptoms, such as hot flashes, vaginal dryness, and mood changes.
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The prophylaxis of osteoporosis in postmenopausal women.
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Short-term use to alleviate menopause-related symptoms.
Dosage
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Adults: The usual dose is 1 tablet (2mg) taken once daily, or as prescribed by your healthcare provider.
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Administration: Take the tablet orally with water, preferably at the same time every day, to ensure consistent results.
Side Effects
Common side effects of Progynova may include:
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Nausea and vomiting.
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Weight gain.
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Breast tenderness and enlargement.
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Withdrawal bleeding.
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Sodium retention with edema (fluid retention).
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Liver function disorders, jaundice.
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Rashes and chloasma (blotchy brown skin patches).
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Headache.
In rare cases, endometrial carcinoma (a type of cancer) may develop in postmenopausal women. If you experience any unusual symptoms, please consult your healthcare provider.
Drug Interactions
Progynova may interact with the following medications:
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Diuretics: May enhance sodium retention effects.
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Antihypertensives: Blood pressure medications may interact with estrogen therapy.
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Liver Enzyme Inducing Drugs: Drugs that induce liver enzymes may reduce the effectiveness of Progynova.
When Not to Use
Do not use Progynova Tablets 2mg if you:
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Are allergic to Estradiol Valerate or any of its components.
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Have a history of blood clots, stroke, or heart disease.
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Have active or a history of breast cancer or endometrial cancer.
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Are pregnant or breastfeeding.
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Have unexplained vaginal bleeding.
Precautions
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Chloasma (Skin Pigmentation): If you have a tendency to develop chloasma (blotchy brown skin patches, particularly on the face), avoid direct sun or ultraviolet light exposure while using Progynova.
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Blood Clots: HRT may increase the risk of blood clots, especially in the first year of use. If you have a history of blood clots, discuss the risks with your healthcare provider.
Warnings
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Risk of Blood Clots: The risk of developing deep vein thrombosis (DVT) is higher in HRT users compared to non-users, particularly in the first year of treatment.
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Heart Disease: HRT is not recommended for women with a history of heart disease or those who are currently experiencing heart problems. Consult your healthcare provider before starting treatment.
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Regular Monitoring: HRT should only be initiated for symptoms that negatively affect quality of life. A careful risk-benefit analysis should be conducted annually, and HRT should only be continued if the benefits outweigh the risks.
Storage
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Storage: Store Progynova at room temperature (between 20°C-25°C), away from direct light, heat, and moisture.
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Keep it out of reach of children and pets.
Quick Tips
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Take the tablet at the same time each day to help you remember.
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Consult your healthcare provider regularly to assess the effectiveness and necessity of continued HRT.
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Avoid sun exposure if you develop skin pigmentation (chloasma) during use.
Doctor Review
Dr. Sarah Ahmed, MBBS, Obstetrician & Gynecologist:
“Progynova 2mg is an effective hormone replacement therapy (HRT) for women experiencing symptoms of menopause. It helps to alleviate common symptoms such as hot flashes and vaginal dryness, while also protecting bone health. However, as with all hormone therapies, it is important to weigh the risks and benefits, especially in terms of cardiovascular health and the risk of blood clots. Progynova should be used under the guidance of a healthcare provider, with regular monitoring for any potential side effects.”
Disclaimer
CureCartDirect provides this information for educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before starting, stopping, or changing any medication.
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